Some organic solvents, resin monomers and related compounds, pigments and occupational exposures in paint manufacture and painting / this publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans which met in Lyon, 18-25 October 1988.
Material type: TextSeries: IARC monographs on the evaluation of carcinogenic risks to humans ; v. 47Publication details: Lyon : International Agency for Research on Cancer, 1989. Description: 535 pISBN: 9283212479Subject(s): Solvents -- adverse effects -- analysis | Epoxy resins -- adverse effects -- analysis | Paint -- adverse effects -- analysis | Environmental exposure | Occupational diseases -- chemically induced | Carcinogenicity tests | Chemical Toxicology and CarcinogenicityNLM classification: QZ 202Abstract: Evaluates the carcinogenic risk to humans posed by exposure to selected organic solvents, resin monomers, and pigments used in paint. Because employment in the paint trades can involve exposure to hundreds of different chemicals, gases, vapours, and dusts, the book also presents a detailed evaluation of the cancer risk posed by overall occupational exposures in paint manufacture and painting. The first half of the book presents separate monographs for six organic solvents, one solvent stabilizer, three resin monomers and modifiers, and two pigments. In view of weaknesses in currently available data, the majority of these substances could not be classified in terms of carcinogenic risk. Dimethylformamide, phenyl glycidyl ether, and antimony trioxide were judged to be possibly carcinogenic to humans. The second half of the book provides a detailed assessment of the likelihood that occupational exposures in paint manufacture and painting can cause cancer in humans. Occupational exposures are evaluated separately for workers engaged in the manufacture of paints and related products, construction painting, painting and related operations in the furniture industry, and painting in the metal industry, including painting of cars and other vehicles. Exposures during lacquering, varnishing, and paint removal and as a result of the preparation of materials prior to painting are also considered. A review of data in humans considers the strength of evidence for toxic effects on the skin and eyes, respiratory tract, nervous system, kidneys, liver and gastrointestinal tract, blood and haematopoietic system, fertility, and the outcome of pregnancy. The most extensive section assesses the design and findings of epidemiological studies of carcinogenicity in the paint trade, including data suggesting an increased risk for cancers at several sites, for leukaemia, and for cancer in children associated with parental exposure. On the basis of this assessment, the book concludes that occupational exposure as a painter causes a significant increase in the risk of several cancers.Item type | Current library | Call number | Copy number | Status | Date due | Barcode |
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Books | WHO HQ READING-RM | IARC SERIAL (Browse shelf(Opens below)) | 1 | Available | 00021983 | |
Books | WHO HQ BORROWABLE-COLL-STACKS | QZ 202 89IA-2 (Browse shelf(Opens below)) | 2 | Available | 00021984 |
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Evaluates the carcinogenic risk to humans posed by exposure to selected organic solvents, resin monomers, and pigments used in paint. Because employment in the paint trades can involve exposure to hundreds of different chemicals, gases, vapours, and dusts, the book also presents a detailed evaluation of the cancer risk posed by overall occupational exposures in paint manufacture and painting. The first half of the book presents separate monographs for six organic solvents, one solvent stabilizer, three resin monomers and modifiers, and two pigments. In view of weaknesses in currently available data, the majority of these substances could not be classified in terms of carcinogenic risk. Dimethylformamide, phenyl glycidyl ether, and antimony trioxide were judged to be possibly carcinogenic to humans. The second half of the book provides a detailed assessment of the likelihood that occupational exposures in paint manufacture and painting can cause cancer in humans. Occupational exposures are evaluated separately for workers engaged in the manufacture of paints and related products, construction painting, painting and related operations in the furniture industry, and painting in the metal industry, including painting of cars and other vehicles. Exposures during lacquering, varnishing, and paint removal and as a result of the preparation of materials prior to painting are also considered. A review of data in humans considers the strength of evidence for toxic effects on the skin and eyes, respiratory tract, nervous system, kidneys, liver and gastrointestinal tract, blood and haematopoietic system, fertility, and the outcome of pregnancy. The most extensive section assesses the design and findings of epidemiological studies of carcinogenicity in the paint trade, including data suggesting an increased risk for cancers at several sites, for leukaemia, and for cancer in children associated with parental exposure. On the basis of this assessment, the book concludes that occupational exposure as a painter causes a significant increase in the risk of several cancers.
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