MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03179cam a2200361 4500 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9241571403 |
| 035 ## - |
|---|
| -- |
(Sirsi) 9241571403 |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
QV 633 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
930707s1993 1 0 eng |
| 242 10 - TRANSLATION OF TITLE BY CATALOGING AGENCY |
|---|
| Title |
Polychlorobiphényles et polychloroterphényles |
| 242 10 - TRANSLATION OF TITLE BY CATALOGING AGENCY |
|---|
| Title |
Difenilos y trifenilos policlorados |
| 245 00 - TITLE STATEMENT |
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| Title |
Polychlorinated biphenyls and terphenyls. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
2nd ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Geneva : |
| Name of publisher, distributor, etc. |
World Health Organization, |
| Date of publication, distribution, etc. |
1993. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
682 p. |
| 440 #0 - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Environmental health criteria ; |
| Volume/sequential designation |
140 |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Summary and evaluation, conclusions and recommendations in French and Spanish. |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Spanish 1st ed. issued as: Publicaci'on cient'ifica / Organizaci'on Panamericana de la Salud ; no. 387. |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc. |
Evaluates the vast body of evidence demonstrating the serious threat to human and environmental health posed by polychlorinated biphenyls (PCBs). These chemicals, which are now ubiquitous in the environment, have been used commercially since 1930 as dielectric and heat-exchange fluids and in a variety of other applications. Over 1,300 studies were critically assessed. The book also contains a brief review of the limited data on polychlorinated terphenyls. A section devoted to the environmental behaviour of PCBs assesses the mechanisms by which these highly persistent chemicals, previously introduced into the environment, are gradually being redistributed towards increased contamination of the marine environment. For the general population, the most important sources of exposure are identified as food items and, for babies, breast-milk. The well-documented signs of poisoning in occupationally-exposed workers are also reviewed. A section devoted to the metabolic fate of PCBs cites evidence of accumulation in the liver and the adipose tissues of various organs, placental transport, fetal accumulation, and distribution to milk. The most extensive section, which runs some 100 pages, evaluates findings from studies of toxicity in experimental animals and in vitro systems. Findings suggest that PCBs are immunosuppressive and act as tumour promoters. An assessment of effects on humans draws upon studies of two large outbreaks of poisoning from contaminated food, and of occupational exposures. Concerning risks to the environment, the report cites reproductive failure in sea mammals as the most important hazard, further concluding that the predicted redistribution of residues towards the marine environment will pose an increasing hazard for sea mammals in the future. A review of the hazards of polychlorinated terphenyls concludes the report. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
eng fre(1ed) spa(1ed). |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
jpn pol(1ed). |
| 550 ## - ISSUING BODY NOTE |
|---|
| Issuing body note |
WHODOC |
| 561 ## - OWNERSHIP AND CUSTODIAL HISTORY |
|---|
| History |
WHO monograph |
| 596 ## - |
|---|
| -- |
4 |
| 650 02 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Environmental exposure. |
| 650 02 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Environmental pollutants. |
| 650 02 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Polychlorinated biphenyls |
| General subdivision |
adverse effects |
| -- |
toxicity. |
| 650 02 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Polychloroterphenyl compounds |
| General subdivision |
adverse effects |
| -- |
toxicity. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) |
|---|
| Topical term or geographic name as entry element |
Chemical Toxicology and Carcinogenicity. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
World Health Organization. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
International Programme on Chemical Safety. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
NLM Classification Scheme |
| Koha item type |
Books |
