000			02922cam a2200301 4500
001			9283212533
020			_a9283212533
035			_a(Sirsi) 9283212533
060			_aQZ 202
111	2		_aIARC Working Group on the Evaluation of Carcinogenic Risks to Humans: Occupational Exposures in Insecticide Application _qand Some Pesticides, _d(1990: _cLyon, France)
245	0	0	_aOccupational exposures in insecticide application and some pesticides / _cthis publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans which met in Lyon, 16-23 October 1990.
260			_aLyon : _bInternational Agency for Research on Cancer, _c1991.
300			_a612 p.
440		0	_aIARC monographs on the evaluation of carcinogenic risks to humans ; _vv. 53
520	3		_aEvaluates the carcinogenic risk to humans posed by occupational exposure during the spraying and application of insecticides. The book also features separate monographs evaluating the carcinogenicity of 17 individual pesticides, including several that have been banned by industrialized countries yet are still used in the developing world. Although some of these pesticides have been in use for more than four decades, evaluations of carcinogenicity were hindered by the sparsity of well-designed epidemiological studies. The first and most extensive monograph evaluates data from descriptive and ecological studies, cohort studies, and case-control studies suggesting an increased risk of cancer, most notably lung cancer, multiple myeloma and other tumours of B-cell origin, in workers exposed to insecticides during their application. On the basis of this evaluation, the book concludes that the spraying and application of nonarsenical insecticides entail exposures that are probably carcinogenic to humans. The remaining monographs evaluate the carcinogenicity of aldicarb, atrazine, captafol, chlordane, DDT, deltamethrin, dichlorvos, fenvalerate, heptachlor, monuron, pentachlorophenol, permethrin, picloram, simazine, thiram, trifluralin, and zitram. Of these, captafol, a fungicide used on plants, for seed treatment, and as a wood preservative, was classified as probably carcinogenic to humans. Atrazine, chlordane, DDT, dichlorvos, heptachlor, and pentachlorophenol were classified as possibly carcinogenic to humans. The remaining pesticides could not be classified on the basis of available data.
550			_aWHODOC
561			_aWHO monograph
596			_a4
650	0	2	_aCarcinogens.
650	0	2	_aInsecticides _xadverse effects _xtoxicity.
650	0	2	_aPesticides _xadverse effects _xtoxicity.
650	0	2	_aOccupational exposure.
650	0	2	_aNeoplasms _xchemically induced.
690			_aChemical Toxicology and Carcinogenicity.
710	2		_aInternational Agency for Research on Cancer.
008			920228s1991 1 0 eng
942			_2NLM _cMONOGRAPH
999			_c9052 _d9052