000			02472cam a2200277 4500
001			9241542985
020			_a9241542985
020			_a522501903x (Russian)
035			_a(Sirsi) 9241542985
060			_aWA 240
245	0	0	_aTetramethrin / _cpublished under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization.
260			_aGeneva : _bWorld Health Organization, _c1990.
300			_a69 p.
440		0	_aEnvironmental health criteria ; _v98
520	3		_aEvaluates the risks to human health and the environment posed by the use of tetramethrin, a synthetic pyrethroid insecticide used in aerosol formulations, emulsifiable concentrates, and mosquito coils exclusively for indoor pest control. A review of data on the environmental behaviour of this insecticide points to rapid abiotic degradation in air and water. Published data also indicate rapid metabolism and excretion in mammals, with no tendency to accumulate in tissues. Concerning effects on organisms in the environment, the report cites laboratory data demonstrating that tetramethrin is highly and acutely toxic to fish and toxic to bees, but has very low toxicitiy for birds. Because tetramethrin is rapidly degraded, and provided its use is limited to buildings, as recommended, this potential for environmental toxicity is unlikely to be realised. The most extensive section evaluates the results of experimental studies of toxicity and carcinogenicity relevant to the assessment of health effects in humans. A review of studies of eye irritation, skin irritation, sensitization, and of investigations for long-term toxic effects and tumorigenic potential yields no evidence of oncogenic or other adverse effects on health. On the basis of this evaluation, the report concludes that tetramethrin, when used as recommended for the indoor control of pests, is highly unlikely to present a hazard to the general population, to those occupationally exposed, or to the environment.
546			_aeng (with summary, evaluation, conclusions, and recommendations in fre) rus.
550			_aWHODOC
561			_aWHO monograph
596			_a4
650	0	2	_aPyrethrins _xadverse effects.
690			_aVector Control and Pesticides.
710	2		_aWorld Health Organization.
710	2		_aInternational Programme on Chemical Safety.
008			900723s1990 1 0 eng
942			_2NLM _cMONOGRAPH
999			_c12024 _d12024