000			03306cam a2200337 4500
020			_a9241208325
035			_a(Sirsi) 9241208325
060			_aWA 701
110	2		_aJoint FAO/WHO Expert Committee on Food Additives.
242	1	0	_aEvaluation des résidus de certains médicaments vétérinaires dans les aliments : _bquarantième rapport du Comité mixte FAO/OMS d'experts des additifs alimentaires [réuni à Genève du 9 au 18 juin 1992]
242	1	0	_aEvaluación de ciertos residuos de fármacos de uso veterinario en los alimentos : _b40 informe del Comité Mixto FAO/OMS de Expertos en Aditivos Alimentarios [se reunió en Ginebra del 9 al 18 de junio de 1992]
245	0	0	_aEvaluation of certain veterinary drug residues in food : _bfortieth report of the Joint FAO/WHO Expert Committee on Food Additives [meeting held in Geneva from 9 to 18 June 1992]
260			_aGeneva : _bWorld Health Organization, _c1993.
300			_a62 p.
440		0	_aWHO technical report series ; _v832
520	3		_aPresents the conclusions of an expert committee commissioned to evaluate the safety of residues of selected veterinary drugs used in food-producing animals, to establish acceptable daily intakes for humans, and to recommend maximum residue limits. On the basis of a rigorous review of all available safety and residue data, the committee establishes international standards intended to promote food safety and facilitate the harmonization of international trade in animal products. The report has two parts. The first explains several methodological issues that are specific to the safety assessment of veterinary drug residues in food. Noting problems posed by the inadequacy of data on veterinary drugs with a long history of use, the report establishes general principles of evaluation and requirements for toxicological data needed to ensure that the safety of these older products is established according to rigorous contemporary standards. The second and most extensive part provides succinct summaries of the toxicological data examined and factors considered when evaluating each substance, identifying any potential hazards to consumer health, and allocating an acceptable daily intake and maximum residue limit. Veterinary drugs considered include five anthelminthics (closantel, flubendazole, ivermectin, tiabendazole, and triclabendazole), two antimicrobial agents (furazolidone and nitrofural), two production aids (bovine somatotropins and ractopamine), and a trypanocide (isometamidium). Acceptable daily intakes and maximum residue limits were established for seven of these drugs. For the remaining substances, the report identifies deficiencies in the available data and specifies the further information required for a re-evaluation.
546			_aeng fre rus spa.
550			_aWHODOC
561			_aWHO monograph
596			_a4
650	0	2	_aDrug residues _xanalysis.
650	0	2	_aDrug therapy _xveterinary.
650	0	2	_aFood contamination.
690			_aNutrition and Food Safety.
710	2		_aWorld Health Organization.
710	2		_aFood and Agriculture Organization of the United Nations.
856			_uhttps://apps.who.int/iris/
856			_uhttps://apps.who.int/iris/
008			930706s1993 1 0 eng
942			_2NLM _cMONOGRAPH
999			_c11301 _d11301