TY - BOOK ED - International Programme on Chemical Safety. ED - United Nations Environment Programme. ED - International Labour Organization. ED - World Health Organization. TI - Butanols - four isomers: 1-butanol, 2-butanol, tert-butanol, isobutanol SN - 9241542659 PY - 1987/// CY - Geneva PB - World Health Organization KW - Butanols N1 - pol published by: Lodz : Institute of Occupational Medicine; Bibliography: p.119-141 N2 - Presents individual monographs on the risks to health and the environment associated with 1-butanol, 2-butanol, tert-butanol, and isobutanol. These butanol isomers, which occur naturally as products of fermentation, are also synthesized from petrochemicals and widely used as solvents and intermediates in chemical industries. Human exposure to high concentrations is primarily occupational, while exposure to low concentrations is mainly through foods in which the isomers occur either naturally or as flavouring agents. Although the butanol isomers can be classified as slightly or practically nontoxic, all isomers, in large amounts, have the ability to induce signs of alcoholic intoxication in both animals and man. The most extensive section of each monograph covers data on biological effects observed in experimental animals, in in vitro test systems, and in cases of accidental occupational exposure in man. Particular attention is given to studies useful in assessing effects on the skin, eyes, and respiratory tract of workers exposed to these chemicals ER -