TY - BOOK AU - AU - Bloom,Barry R. AU - Lambert,Paul Henri TI - The vaccine book SN - 0121072584 AV - QR189 .V233 2003 U1 - 615/.372 21 PY - 2003/// CY - Amsterdam PB - Academic Press KW - Vaccines N1 - Global Burden of Disease A The Burden of Vaccine-Preventable Diseases / Maureen Birmingham, Claudia Stein -- Cost Effectiveness of Immunization: Asking the Right Questions / Ruth E. Levine -- Potential and Existing Impact of Vaccines on Disease Epidemiology / Elizabeth Miller -- Ch.2 Immunology A Basic Immunology of Vaccine Development / Robert A. Seder, John R. Mascola -- B Immunological Requirements for Vaccines to Be Used in Early Life / Claire-Anne Siegrist -- Ch.3 Trial Design for Vaccines A Clinical Development of New Vaccines: Phase 1 and 2 Trials / W. Ripley Ballou B Phase 3 Studies of Vaccines / John D. Clemens, Hye-Won Koo -- Ch.4 Ethics and Vaccines / Ruth Macklin, Brian Greenwood -- Ch.5 Understanding Microbial Pathogenesis as a Basis for Vaccine Design -- A Bacteria / B. Brett Finlay -- B Disease-Oriented Approach to the Discovery of Novel Vaccines / Jeffrey N. Weiser, Elaine I. Tuomanen -- C Immunological Memory and Vaccines against Acute Cytopathic and Noncytopathic Infections / Rolf M. Zinkernagel -- D Parasitic Diseases, with an Emphasis on Experimental Cutaneous Leishmaniasis / Pascal Launois, Heike Voigt, Alain Gumy, Abraham Aseffa, Fabienne Tacchini-Cottier, Martin Rocken, Jacques A. Louis -- Ch.6 Disease States and Vaccines: Selected Cases -- A Introduction / Stanley A. Plotkin -- B Polio / Ciro A. De Quadros C Rubella / Jennifer M. Best, Siobhan O'Shea -- D Pertussis / Stefania Salmaso E Rotavirus / Joseph S. Bresee, Roger I. Glass, Umesh Parashar, Jon Gentsch -- F AIDS Vaccines: Challenges and Prospects / Elisa I. Choi, Norman L. Letvin -- G Pneumococcus, Pneumococcal Disease, and Prevention / Jill G. Hackell -- H Tuberculosis / Douglas B. Young I Malaria / Stephen L. Hoffman, Thomas L. Richie J Human Papillomaviruses / Lutz Gissmann K Helicobacter pylori / Giuseppe Del Giudice, Rino Rappuoli -- L Genome-Based Approach for a Vaccine against Neisseria meningitidis / Vega Masignani, Mariagrazia Pizza, Rino Rappuoli -- Ch.7 Economics of Vaccines: From Vaccine Candidate to Commercialized Product / Amie Batson, Sarah Glass, Erica Seiguery -- Ch.8 Vaccine Safety: Real and Perceived Issues / Neal A. Halsey -- Ch.9 Introduction of New Vaccines in the Healthcare System / Edward Kim Mulholland, Bjarne Bjorvatn -- Ch.10 Future Challenges for Vaccines and Immunization / Paul-Henri Lambert, Barry R. Bloom ER -