TY - BOOK AU - Pollard,Andrew J. AU - Maiden,Martin C.J. TI - Meningococcal vaccines: methods and protocols SN - 0896038017 PY - 2001/// CY - Totowa, N.J. PB - Humana Press KW - Meningococcal vaccines KW - therapeutic use KW - Meningitis, Meningococcal KW - drug therapy N1 - Companion volume to: Meningococcal disease; Ch.1 Meningococcal Vaccines and Vaccine Developments -- Ch. 2 Immune Response and Host-Pathogen Interactions -- Ch. 3 Purification of Capsular Polysaccharide -- Ch.4 Protein-Polysaccharide Conjugation -- Ch.5 N-Propionylation -- Ch.6 Outer Membrane Protein Purification -- Ch.7 Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease -- Ch.8 Methods for Manipulation of Transferrin-Binding Proteins -- Ch.9 Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins -- Ch.10 Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics -- Ch.11 Construction of porA Mutants -- Ch.12 Construction of LPS Mutants -- Ch.13 Recombinant Proteins in Vaccine Development -- Ch.14 Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries -- Ch.15 Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity -- Ch.16 Early Experiences with Nasal Vaccines against Meningococcal Disease -- Ch.17 Animal Models for Meningococcal Disease -- Ch.18 Determination of Antibody Responses to Meningococcal Antigens by ELISA -- Ch.19 Immunoblot Analysis of Sera from Patients and Vaccinees -- Ch.20 Serogroup B and C Serum Bactericidal Assays -- Ch.21 A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers -- Ch.22 Whole-Blood Model -- Ch.23 Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry -- Ch.24 T-Cell Responses Against Meningococcal Antigens -- Ch.25 CD4 T-Cell Epitope Mapping -- Ch.26 Epitope Mapping -- Ch.27 Meningococcal Vaccine Trials -- Ch.28 The Introduction of Group C Conjugate Meningococcal Vaccine into the UK ER -