TY - BOOK ED - IARC Working Group on the Evaluation of the Carcinogenic Risk of Chemicals to Humans: some Naturally Occurring and Synthetic Food Components ED - International Agency for Research on Cancer. TI - Some naturally occurring and synthetic food components, furocoumarins and ultraviolet radiation SN - 9283212401 PY - 1986/// CY - Lyon PB - International Agency for Research on Cancer KW - Carcinogens, Environmental KW - Food additives KW - Psoralens KW - Food contamination KW - Ultraviolet rays N2 - A critical review of data on carcinogenicity for 15 common food additives and contaminants and five furocoumarins used in the photochemotherapy of skin disorders and in suntanning products, fragrances, and other cosmetics. Separate monographs are presented for four naturally occurring food toxins (bracken fern, citrinin, patulin, and rugulosin); four widely used additives (benzyl acetate, butylated hydroxyanisole, butylated hydroxytoluene, and potassium bromate); and seven mutagenic heterocyclic compounds that may be formed during cooking of food. Some of the additives considered are also widely used in cosmetics, especially lipsticks and eyeshadows. The book also features five monographs on selected furocoumarins used, or under investigation for use, in the treatment of several skin diseases, including psoriasis, vitiligo, and the T-cell lymphoma mycosis fungoides. Since the clinical and suntanning uses of the furocoumarins depend on concomitant exposure to ultraviolet radiation, the book includes a useful appendix summarizing data from case reports, animal studies, and epidemiological research valuable in assessing the association between exposure to sunlight and the development of skin cancer ER -