Principles for evaluating health risks from chemicals during infancy and early childhood : the need for a special approach / published under the joint sposorship of the United Nations Environment Programme, the International Labour Organisation, the World Health Organization, and on behalf of the Commission of the European Communities.
Material type:
TextSeries: Environmental health criteria ; 59Publication details: Geneva : World Health Organization, 1986. Description: 73 pISBN: 9241542594Subject(s): Chemicals -- adverse effects -- in infancy and childhood | Health status indicators | Environmental exposure | Pharmacology, Toxicology and Clinical TechnologyNLM classification: WA 30Dissertation note: Bibliography: p.53-66. Abstract: Elaborates basic principles for the evaluation of chemical toxicology that are specific to the physiological characteristics of infants and young children. Principles of evaluation, which were worked out by 46 leading experts, are based on a thorough review of data on postnatal physiology, metabolism, and the special factors governing exposure in this age group, including behavioural and cultural conditions. Following background information on relevant features of postnatal morphology, biochemistry, and physiology, chapters assess the kinetics of absorption, biotransformation, and elimination and point out ways in which certain conditions of postnatal development will influence the effects of chemicals on different organs and systems. The book concludes with a discussion of factors that can assist in the identification of children at risk.
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chi of nos. 35, 36, 37, 38, 46, 47 and 59 published in one volume by: Beijing : Chinese Academy of Preventive Medicine.
Bibliography: p.53-66.
Elaborates basic principles for the evaluation of chemical toxicology that are specific to the physiological characteristics of infants and young children. Principles of evaluation, which were worked out by 46 leading experts, are based on a thorough review of data on postnatal physiology, metabolism, and the special factors governing exposure in this age group, including behavioural and cultural conditions. Following background information on relevant features of postnatal morphology, biochemistry, and physiology, chapters assess the kinetics of absorption, biotransformation, and elimination and point out ways in which certain conditions of postnatal development will influence the effects of chemicals on different organs and systems. The book concludes with a discussion of factors that can assist in the identification of children at risk.
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