TY  - BOOK
ED  - World Health Organization.
ED  - International Programme on Chemical Safety.
TI  - Tri-n-butyl phosphate
SN  - 9241571128
PY  - 1991///
CY  - Geneva
PB  - World Health Organization
KW  - Phosphoric acid esters
KW  - adverse effects
KW  - toxicity
N1  - Translations in French and Spanish of chapters 1, 10 and 11
N2  - Evalutes risks to human health and the environment posed by the production and use of tri-n-butyl phosphate. Tri-n-butyl phosphate is widely used worldwide as a solvent for cellulose esters, lacquers, and natural gums, as a primary plasticizer in the manufacture of plastics and vinyl resins, in the formulation of fire-resistant aircraft hydraulic fluids, and as an antifoaming agent, mainly in paper manufacturing  plants. Although tri-n-butyl phosphate has been widely detected in air, water, sediment, and biological tissues, the review notes that concentrations are usually very low. Workers involved in aircraft maintenance and exposed during the manipulation of hydraulic fluids are regarded as the largest occupational group at risk. In view of several weaknesses in available experimental data, the report was unable to reach firm conclusions concerning the risks posed by tri-n-butyl phosphate as a potential carcinogen, neurotoxic agent, or dermal sensitizer, though a neurotoxic effect comparable to organophosphate-induced delayed neuropathy was judged unlikely. The report concludes that the production and use of tri-n-butyl phosphate pose a low risk for the environment and for the general population, and that the likelihood of long-term effects in occupationally exposed workers is small
UR  - http://apps.who.int/iris/
ER  -