Summary and evaluation, conclusions and recommendations in French and Spanish.

Evaluates the risks to human health and the environment posed by 1,3-dichloropropene, 1,2-dichloropropane and mixtures of these chemicals. Since the two compounds and mixtures have been widely used in agriculture as pre-plant fumigants applied by soil injection, the report gives particular attention to studies investigating behaviour in soil, risks of leaching and groundwater contamination, uptake by food crops, residues detected in drinking-water and food, and risks to agricultural workers and the general population. Over 300 studies, including proprietary toxicological data from the manufacturers, were critically assessed. The report concludes that, when used at the recommended rate, 1,3-dichloropropene is unlikely to attain levels of environmental significance. Risks to the general population were judged negligible. Concerning occupational hazards, the report cites evidence, largely from case reports of poisoning, underscoring the need to follow appropriate safety precautions. The report concludes that 1,2-dichloropropane poses a negligible risk to the general population. When used at the recommended rate, the compound is unlikely to attain levels of environmental significance. For workers, the compound is judged unlikely to pose a hazard, provided good work practices, hygienic measures, and safety precautions are followed. Data on mixtures of dichloropropenes and dichloropropane are evaluated in the final monograph. This technical mixture previously enjoyed wide use as a soil nematocide before planting. Citing evidence of a significant potential for 1,2-dichloropropane derived from this mixture to leach from soil and contaminate well water and groundwater, the report recommends that mixtures of dichloropropenes and dichloropropane should not be used as a soil fumigant.

eng.

WHODOC

WHO monograph

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