Occupational exposures in petroleum refining : crude oil and major petroleum fuels / this publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans which met in Lyon, 1-8 March 1988.
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TextSeries: IARC monographs on the evaluation of carcinogenic risks to humans ; v. 45Publication details: Lyon : International Agency for Research on Cancer, 1989. Description: 322 pISBN: 9283212452Subject(s): Petroleum -- adverse effects | Environmental exposure | Occupational diseases | Neoplasms -- etiology | Cancer and its ControlNLM classification: QZ 202Abstract: Presents six separate monographs assessing the carcinogenic risks to humans posed by occupational exposures in petroleum refining, by exposure to crude oil, and by exposure to four of the main saleable fuel products of petroleum refining. Occupational exposures in petroleum refining are evaluated in the first and most extensive monograph. Following a brief historical review of the industry's evolution and development of new refining processes, the monograph provides a detailed description of each of the main manufacturing processes, including information on purpose and nature, operating conditions, and unit feedstocks and products. Against this background, experimental data are evaluated as they pertain to occupational exposures to different crude oils, intermediate process streams, petroleum products, and a variety of process chemicals, fuel additives and other substances that occur in petroleum refineries. Experimental data on the carcinogenicity or other related effects of the main process streams are assessed in view of their relevance to both the overall evaluation of carcinogenicity of occupational exposures in petroleum refineries and the evaluation of products that contain these streams as major components. The evaluation also considers human data collected in ten separate cohort studies conducted in the USA, two from Canada, and one from the United Kingdom. On the basis of the evidence assessed, the monograph concludes that occupational exposures in petroleum refining are probably carcinogenic to humans. The carcinogenicity of crude oil is evaluated in the second monograph, which concludes that crude oil cannot be classified as to its carcinogenicity to humans. The remaining monographs review data for automotive and aviation gasoline, jet fuels, diesel fuels, including marine diesel fuels, and other fuel oils used as burner fuel for domestic and industrial heating, and for raising steam for electricity generation and marine propulsion. Gasoline is classified as possibly carcinogenic to humans, jet fuels and distillate diesel fuels could not be classified, marine diesel fuel and residual fuel oils are classified as possibly carcinogenic to humans, and distillate fuel oils could not be classified as to their carcinogenicity to humans.
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Presents six separate monographs assessing the carcinogenic risks to humans posed by occupational exposures in petroleum refining, by exposure to crude oil, and by exposure to four of the main saleable fuel products of petroleum refining. Occupational exposures in petroleum refining are evaluated in the first and most extensive monograph. Following a brief historical review of the industry's evolution and development of new refining processes, the monograph provides a detailed description of each of the main manufacturing processes, including information on purpose and nature, operating conditions, and unit feedstocks and products. Against this background, experimental data are evaluated as they pertain to occupational exposures to different crude oils, intermediate process streams, petroleum products, and a variety of process chemicals, fuel additives and other substances that occur in petroleum refineries. Experimental data on the carcinogenicity or other related effects of the main process streams are assessed in view of their relevance to both the overall evaluation of carcinogenicity of occupational exposures in petroleum refineries and the evaluation of products that contain these streams as major components. The evaluation also considers human data collected in ten separate cohort studies conducted in the USA, two from Canada, and one from the United Kingdom. On the basis of the evidence assessed, the monograph concludes that occupational exposures in petroleum refining are probably carcinogenic to humans. The carcinogenicity of crude oil is evaluated in the second monograph, which concludes that crude oil cannot be classified as to its carcinogenicity to humans. The remaining monographs review data for automotive and aviation gasoline, jet fuels, diesel fuels, including marine diesel fuels, and other fuel oils used as burner fuel for domestic and industrial heating, and for raising steam for electricity generation and marine propulsion. Gasoline is classified as possibly carcinogenic to humans, jet fuels and distillate diesel fuels could not be classified, marine diesel fuel and residual fuel oils are classified as possibly carcinogenic to humans, and distillate fuel oils could not be classified as to their carcinogenicity to humans.
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