ita In Quaderni di Sanità Pubblica. - Anno 14, no. 72 (ottobre 1991) and Il Nuovo Bollettino di Farmacologia Clinica vol. 14 n.4 Luglio-Agosto 1990.

Partial contents: 13. Model list of essential drugs. 6th list.

Presents and explains the sixth model list of essential drugs issued by WHO as part of its efforts to extend the benefits of modern drugs to the worlds population. Intended to guide the selection of drugs in countries where the need is great and the resources are small, the list identifies a core group of prophylactic and therapeutic substances judged capable of meeting the vast majority of health needs and thus deserving priority in purchasing decisions and procurement schemes. The first half of the report provides updated information on several components of national drug policy necessary to assure that essential drugs, corresponding to essential health needs, are available at all times in adequate amounts and in the proper dosage. The sixth WHO model list of essential drugs is then presented, together with an explanation of changes made when revising the list. Organized according to therapeutic group, the list includes information on route of administration, dosage forms, and strengths for each of 275 drugs. To qualify for inclusion in the list, a drug must be supported by sound and adequate data demonstrating safety, efficacy, and consistent performance in a variety of medical settings. Factors of cost, stability, quality control, and international availability were also considered. Revisions in the list, which were agreed upon by an international group of experts, reflect changes in disease patterns, advances in drug development, and experiences in the use of specific preparations. Revisions also alert readers to cases where advances in pharmacology have made certain drugs obsolete. In total, six substances have been withdrawn from the list.

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WHODOC

WHO monograph

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